HERMANN TEST CODE:
CPT CODE: 85247
SPECIMEN REQUIREMENT: 5 mL blood (minimum 4.5 ml), blue top tube (sodium citrate), mixed well.
TEST AVAILABILITY: Sent out by Hermann Laboratory to Methodist Hospital Coagulation Laboratory. Reporting time in less than 7 days.
METHODOLOGY: Immunoelectrophoresis
CLINICAL UTILIZATION: Subtyping von Willebrand's Disease
REFERENCE RANGE: Normal gel pattern as normal control
INTERPRETATION:
In von Willebrand's disease (vWD), there is abnormal multimeric structure. The spectrum of vWD may involve qualitative and /or quantitative abnormalities of plasma and /or platelet von Willebrand Factor (vWF).
Multimer analysis has formed the basis of subtype classification of vWD. As such, von Willebrand Multimer Analysis is only needed after a diagnosis of von Willebrand's disease has been established using the more common tests such as: vWF:RCo, vWF:Ag, F VIII:C, PTT, bleeding time.
LITERATURE:
