Image
|
Slide # |
Tissue |
Mag |
Feature |
 |
1 |
Vulva |
Gross |
Erythroplakia nd leukoplakia c/w carcinoma in situ. |
 |
2 |
|
|
Junction of relatively normal with dysplastic epithelium: Note mitoses above the basal layer, disordered maturation, and nuclear abnormalities, but that there is some maturation beneath the keratin layer. |
 |
3 |
|
|
Carcinoma in situ, lack of maturation and nuclear atypia extends throughout the epithelium (excluding keratin layer) and the basement membrane is intact. Note koilocytes (cells with hyperchromatic, irregular nuclei surrounded by halo). |
 |
4 |
|
|
Carcinoma in situ, note mitosis in prickle cell layer and koilocyte (cell with hyperchromatic, irregular, "rasinoid" nucleus with halo). |
 |
6 |
Squamous cell carcinoma |
Gross |
Ulcerated, nodular lesion |
 |
7 |
|
LP |
Junction of hyperplastic epithelium with carcinoma |
 |
8 |
|
MP |
Nests of carcinoma, some with clear cytoplasm |
 |
9 |
|
MP |
Well differentiated squamous cell carcinoma with keratin pearls |
 |
11 |
|
Gross |
Mastectomy specimen with breast carcinoma extending into overlying skin, note biopsy site. |
 |
12 |
Breast |
Gross |
Cross section of breast with scirrhous carcinoma |
 |
13 |
|
LP |
Breast carcinoma (infiltrating ductal carcinoma) with marked desmoplastic response. |
 |
14 |
|
MP |
Cords of breast carcinoma with marked desmoplastic response |
 |
15 |
Breast carcinoma |
|
Solid nests and glands invading adipose tissue |
 |
16 |
|
HP |
Solid nests with few small gland lumens in breast carcinoma |
 |
17 |
Breast carcinoma |
MP |
|
 |
19 |
Brain |
Gross |
Brain with metastatic carcinoma, note flattened gyri and compressed sulci and ventricle |
 |
20 |
|
LP |
Metastatic adenocarcinoma to brain |
 |
21 |
Adenocarcinoma |
HP |
Note columnar cells with hyperchromatic enlarged nuclei |
 |
23 |
Mediastinal lymph nodes with metastatic carcinoma |
Gross |
Note anthracosis (black pigment) and that the whitish gray or tan tumor begins in subcapsular region |
 |
24 |
|
|
Metastatic carcinoma to lymph node |
 |
25 |
|
|
Metastatic carcinoma |
 |
29 |
Kidney |
Gross |
Kidney with renal cell carcinoma with direct extension through capsule into perirenal fat |
 |
31 |
Breast |
Gross |
Section of carcinoma of breast with direct extension into overlying skin |
 |
32 |
Lymph Nodes |
Gross |
Metastatic carcinoma to para-aortic lymph nodes: note one ureter dilated from compression by the enlarged lymph nodes |
 |
33 |
Vertebra |
Gross |
Vertebra with metastatic tumor |
 |
34 |
Ribs |
Gross |
Ribs with metastatic tumor |
 |
35 |
|
Gross |
Mesentery with seeding or implantation. (occurs most often with malignancy, but rupture of benign tumors can also seek abdominal cavity) |