Pathology Review Carousel 3

Pathology Review Carousel 3 Pathology Review Carousel 3
Immunopathology

For all of these images, left click to enlarge.

Image
Slide # Tissue Mag Feature

195A Lung, asthma LP Hyperplasia of mucous glands

195B Lung, asthma MP Hyperplastic glands; hypertrophy of smooth muscle

195C Lung, asthma Thickened basementn membrane, smooth muscle, inflammatory cells

195D Lung, asthma Thickened basement membrane; inflammatory cells

195E Lung, asthma Goblet cell metaplasia in bronchial epithelium

195G Lung, asthma Thickened basement membrane; lymphocytes, eosinophils, plasma cells

65A Kidney, acute and chronic rejection LP hemorrhage, loss of tubules

65B Kidney, acute and chronic rejection Endothelial proliferation (acute vascular rejection)

65C Kidney, acute and chronic rejection Interstitial fibrosis; scattered cellular infiltrate

65D Kidney, acute and chronic rejection Fibrinoid necrosis of small vessel and capillary loops in glomerulus

65E Kidney, acute and chronic rejection Hemorrhage. Thickened, fibrotic wall of vessel (chronic rejection)

65F Kidney, acute and chronic rejection Endovasculitis (acute vascular rejection)

99A Kidney, systemic lupus erythematosus MP Two hypercellular glomeruli. Large glomerulus in center shows increased lobulation of the glomerular capillary tuft and closure of peripheral capillary loops. Tubules separated by inflammatory cells in interstitium.

99C Kidney, systemic lupus erythematosus MP Two glomeruli present. The glomerulus in the upper hypercellular. There is patchy interstitial inflammation.

99E Kidney, systemic lupus erythematosus HP Glomerulus. Peripheral capillary loops at 5:00 in the capillary tuft show fibrin thrombi in lumens. At 7:00 in the capillary tuft there are nuclear fragments indicating focal necrosis in the tuft.

99D Kidney, systemic lupus erythematosus HP Hypercellular glomerulus. Wire-loop lesion (subendothelial deposition of antigen-antibody complexes causing thickening and eosinophilia of capillary walls) particularly prominent at 2-3:00. At 5:00 there is a thrombus in a capillary loop.

99H Kidney, systemic lupus erythematosus HP Hypercellular glomerulus at left. Just to the right of center at the bottom is an arteriole containing a fibrin thrombus. Inflammatory cells in interstitium.

99I Kidney, systemic lupus erythematosus MP 2 hypercellular glomeruli. upper glomerulus shows wire-loops. Lower glomerulus shows fibrinoid necrosis of glomerular arteriole.

34A Joint, rheumatoid synovitis Papillary villous thickening of proliferative synovium (pannus). Normally the synovium is a thin, single layer of cells.

34B Joint, rheumatoid synovitis Area with more mononuclear cell infiltrate of lymphocytes and plasma cells.

180A Thyroid, Hashimotos's Disease Broad bands of fibrous connective tissue divide residual thyroid follicles.

180B Thyroid, Hashimoto's Disease Lymphoid follicles, as well as diffuse infiltrate of lymphoid cells, are present.

180C Thyroid, Hashimoto's Disease HP Lympoid follicle with a germinal center.

180D Thyroid, Hashimoto's Disease Scattered lymphocytes and thyroid follicles.

180E Thyroid, Hashimoto's Disease Infiltrate of lymphocytes and plasma cells with some lymphocyte infiltrating into thyroid follicles.

180F Thyroid, Hashimoto's Disease HP Infiltrating lymphocytes and plasma cells.

184A Skin, Arthus reaction LP Full thickness of skin with numerous hair follicles and vessels with dense inflammatory infiltrate.

184B Skin, Arthus reaction Vessel with inflammatory cells lumen and through wall (vasculitis)

184C Skin, Arthus reaction Neutrophils and nuclear debris (dust) throughout wall of vessel.

184D Skin, Arthus reaction HP 184C, vasculitis

Image	Slide #	Tissue	Mag	Feature
	195A	Lung, asthma	LP	Hyperplasia of mucous glands
	195B	Lung, asthma	MP	Hyperplastic glands; hypertrophy of smooth muscle
	195C	Lung, asthma		Thickened basementn membrane, smooth muscle, inflammatory cells
	195D	Lung, asthma		Thickened basement membrane; inflammatory cells
	195E	Lung, asthma		Goblet cell metaplasia in bronchial epithelium
	195G	Lung, asthma		Thickened basement membrane; lymphocytes, eosinophils, plasma cells
	65A	Kidney, acute and chronic rejection	LP	hemorrhage, loss of tubules
	65B	Kidney, acute and chronic rejection		Endothelial proliferation (acute vascular rejection)
	65C	Kidney, acute and chronic rejection		Interstitial fibrosis; scattered cellular infiltrate
	65D	Kidney, acute and chronic rejection		Fibrinoid necrosis of small vessel and capillary loops in glomerulus
	65E	Kidney, acute and chronic rejection		Hemorrhage. Thickened, fibrotic wall of vessel (chronic rejection)
	65F	Kidney, acute and chronic rejection		Endovasculitis (acute vascular rejection)
	99A	Kidney, systemic lupus erythematosus	MP	Two hypercellular glomeruli. Large glomerulus in center shows increased lobulation of the glomerular capillary tuft and closure of peripheral capillary loops. Tubules separated by inflammatory cells in interstitium.
	99C	Kidney, systemic lupus erythematosus	MP	Two glomeruli present. The glomerulus in the upper hypercellular. There is patchy interstitial inflammation.
	99E	Kidney, systemic lupus erythematosus	HP	Glomerulus. Peripheral capillary loops at 5:00 in the capillary tuft show fibrin thrombi in lumens. At 7:00 in the capillary tuft there are nuclear fragments indicating focal necrosis in the tuft.
	99D	Kidney, systemic lupus erythematosus	HP	Hypercellular glomerulus. Wire-loop lesion (subendothelial deposition of antigen-antibody complexes causing thickening and eosinophilia of capillary walls) particularly prominent at 2-3:00. At 5:00 there is a thrombus in a capillary loop.
	99H	Kidney, systemic lupus erythematosus	HP	Hypercellular glomerulus at left. Just to the right of center at the bottom is an arteriole containing a fibrin thrombus. Inflammatory cells in interstitium.
	99I	Kidney, systemic lupus erythematosus	MP	2 hypercellular glomeruli. upper glomerulus shows wire-loops. Lower glomerulus shows fibrinoid necrosis of glomerular arteriole.
	34A	Joint, rheumatoid synovitis		Papillary villous thickening of proliferative synovium (pannus). Normally the synovium is a thin, single layer of cells.
	34B	Joint, rheumatoid synovitis		Area with more mononuclear cell infiltrate of lymphocytes and plasma cells.
	180A	Thyroid, Hashimotos's Disease		Broad bands of fibrous connective tissue divide residual thyroid follicles.
	180B	Thyroid, Hashimoto's Disease		Lymphoid follicles, as well as diffuse infiltrate of lymphoid cells, are present.
	180C	Thyroid, Hashimoto's Disease	HP	Lympoid follicle with a germinal center.
	180D	Thyroid, Hashimoto's Disease		Scattered lymphocytes and thyroid follicles.
	180E	Thyroid, Hashimoto's Disease		Infiltrate of lymphocytes and plasma cells with some lymphocyte infiltrating into thyroid follicles.
	180F	Thyroid, Hashimoto's Disease	HP	Infiltrating lymphocytes and plasma cells.
	184A	Skin, Arthus reaction	LP	Full thickness of skin with numerous hair follicles and vessels with dense inflammatory infiltrate.
	184B	Skin, Arthus reaction		Vessel with inflammatory cells lumen and through wall (vasculitis)
	184C	Skin, Arthus reaction		Neutrophils and nuclear debris (dust) throughout wall of vessel.
	184D	Skin, Arthus reaction	HP	184C, vasculitis