Image
|
Slide # |
Tissue |
Mag |
Feature |
 |
34 |
Kidney |
Gross |
Wilms tumor. The tumor is within sharply demarcated from the kidney. Hemorrhage and necrosis is not as extensive as in neuroblastoma. |
 |
35 |
Kidney |
Gross |
Wilms tumor. |
 |
36 |
Kidney |
Gross |
Wilms tumor. Fish flesh appearance. Cystic degeneration may occur. |
 |
37 |
Kidney |
MP |
Wilms tumor. Epithelium and blastema. |
 |
38 |
Kidney |
LP |
Wilms tumor. Trimophic pattern with epithelial, stromal and blastemal components. While one component may dominate, Wilms tumor contains both epithelial and stromal elements. |
 |
39 |
Same |
LP |
Same. |
 |
40 |
Same. |
LP |
Same. |
 |
41 |
Kidney |
HP |
Wilms tumor. Blastema, central focus of stroma. |
 |
42 |
Kidney |
HP |
Wilms tumor. Prognosis can be predicted by histologic appearance. No anaplastic, rhabdoid or clear cell components indicated a favorable prognosis. |
 |
44 |
Infant |
Gross |
Patient preoperatively with sacrococcygeal teratoma. Teratomas are usually gonadal or midline in sacrococcygeal region, or retroperitoneum. Tissue derived from different germ layers. |
 |
46 |
Lung |
Gross |
Cystic adenomatoid malformation. One of the types of cystic disease of the lung. The other two are bonchogenic and lymphangiectasis. |
 |
47 |
Lung |
LP |
Cystic adenomatoid malformation. Numerous small cystic spaces lined by mucinous, "gastric-like" epithelium. |
 |
48 |
Lung |
MP |
Cystic adenomatoid malformation. |
 |
49 |
Lung |
HP |
Cystic adenoatoid malformation. "Gastric-like" epithelium. |
 |
51 |
Umbilical Cord |
Gross |
Single umbilical artery. |
 |
53 |
Brain |
Gross |
Intraventricular hemorrhage with extension to the posterior fossa subarachnoid space. Intraventricular (germinal matrix) hemorrhage usually affect small premature infants because the vessels of the subependymal germinal matrix are susceptible to anoxia. |
 |
54 |
Brain |
MP |
Germinal matrix hemorrhage. Cellular subependyma persists until 36-37 weeks gestation. |
 |
55 |
Chest organs |
Gross |
Tracheo-esophageal fistula with esophageal atresia. |
 |
56 |
Diverticulum from ileum |
Gross |
Meckel's diverticulum with ulcer. 50% are symptomatic (bleeding, intestinal obstruction), usually before 2 years of age. Ulcer often related to presence of gastric epithelium. |
 |
57 |
Colon |
Gross |
Hirschsprung's disease. A ganglionosis of segment or entire colon. A ganglionic distal portion is constricted and the proximal part is dilated. |
 |
58 |
Colon |
HP |
Hirschsprung's disease. Note absence of ganglion cells from the intermuscular (Auerbach) plexus. (Ganglion cells would also be absent in submucosal (Meissner) plexus.) |
 |
59 |
Body cavity |
Gross |
Diaphragmatic hernia, with unilateral pulmonary hypoplasia. |
 |
60 |
Kidney |
Micro |
CMV (cytomegalovirus). |
 |
61 |
|
|
Right ventricular landmarks. |
 |
62 |
|
|
Left ventricular landmarks. |
 |
63 |
|
|
Valve incompetent foramen ovale. |
 |
64 |
|
|
Normal kidneys in a newborn baby (cortex and medulla well visualized) with unilateral double ureter. |
 |
65 |
|
|
Horshoe kidney |
 |
66 |
|
|
Posterior urethral valves with hypertrophic urinary bladder, bilateral hydroureter and atrophic kidneys. |
 |
67 |
|
|
Bilateral renal dysplasia (cysts present in one kidney). |
 |
68 |
|
|
Bilateral renal dysplasia with lower urinary tract obstruction bilateral hydroureter and bilateral hydronephrosis. |
 |
69 |
|
|
Cystic renal dysplasia. |
 |
70 |
|
|
Autosomal recessive "Infantile" polycystic kidney. |
 |
71 |
|
|
Medullary cystic disease. |
 |
72 |
|
|
Autosomal dominant "Adult" polycystic kidney disease - External surface. |
 |
73 |
|
|
Autosomal dominant "Adult" polycystic kidney disease - Cut surface. |
 |
74 |
|
|
Simple cyst with hemorrhage in an otherwise normal kidney. |
 |
75 |
|
|
End stage kidney with multiple cysts (acquired cystic renal disease). |