Image	Slide #	Tissue	Mag	Feature
	1	Lung	LP	Hyaline Membrane Disease. Results from lack of surfactant and consequent pulmonary instability. Within each lobule, the expanded respiratory bronchiole and alveolar ducts are lined by eosinophilic hyaline membranes and are surrounded by collapsed air spaces.
	2	Lung	MP	HMD. Central alveolar duct lined by hyaline membrane and surrounded by collapsed alveolar spaces.
	3	Lung	HP	HMD. Hyaline membranes (which are not distinctive or specific) and close view of immature lung with thick septa.
	5	Lung	LP	Bronchopulmonary dysplasis. Represents the effect of prolonged ventilation (barotrauma) and high concentration of oxygen on neonatal lung which initially had HMD (or other injury). Characteristic features are irregular aeration (some areas dilated and others collapsed) and alveolar septa thickened by mononuclear inflammatory cells and fibroblasts.
	6	Lung	MP	Bronchopulmonary dysplasia. Poorly aerated areas with alveolar septa thickened by fibroblasts and mononuclear inflammatory cells.
	7	Lung	LP	Bronchopulmonary dysplasia. Alveolar spaces expanded, but septa thickened by edema, mononuclear inflammatory cells and fibroblasts.
	8	Lung	MP	Bronchopulmonary dysplasia. Squamous metaplasia of bronchioles.
	10	Lung	LP	Massive aspiration. Occurs in mature or postmature infant with intrauterine distress. Note mature lung (thin septa) with large numbers of squamous epithelial cells and meconium within the air spaces which indicates the diagnosis.
	11	Lung	MP	Massive aspiration. Meconium is more easily seen. Numerous squamous epithelial cells also are present.
	13	Lung	MP	Pneumonia of intrauterine origin. Again note the mature lung. The air spaces contain some squamous epithelial cells and loose collection of neutrophils without accompanying fibrin. The lack of fibrin distinguishes pneumonia of intrauterine origin from postnatally acquired pneumonia.
	14	Lung	MP	Same.
	15	Lung	HP	The thin septa with inconspicuous epithelium and one narrow capillary. Some squamous epithelial cells within air spaces.
	16	Lung	HP	Pneumonia of intrauterine origin. Neutrophils without fibrin. The inflammatory cells enter the fetal airway from the infected amniotic sac.
	18	Fetal membranes	MP	Acute chorioamnionitis. A dense purulent (neutrophilic) imflammatory infiltrate occupies the chorion with extension into the amnion but with preservation of the amniotic epithelium. Represents an ascending infection from the birth canal, usually accompanying premature rupture of the membranes.
	19	Same		Same. Potential sequelae are premature labor, prematurity and fetal infection.
	21	Pancreas	LP	Cystic fibrosis, mucoviscidosis. (Most common metabolic disorder in childhood. Abnormal transport of cellular chloride. Inspissated secretions of exocrine glands.) Pancreatic acini are dilated with intraacinar inspissated secretion smaking distinction of acini from ducts difficult. There is interstitial fibrosis.
	22	Pancreas	MP	Cystic fibrosis. Atrophy of glands, fibrosis, and preservation of islets.
	23	Same		Same.
	24	Same	MP	Cystic fibrosis. Dilated acini with inspissate secretions.
	26	Neuroblastoma	Gross	Neuroblastoma. Soft, white, with hemorrhage and focal necrosis.
	27	Same	Gross	Neuroblastoma. Encapsulated gray-white tumor with hemorrhage and yellow foci of calcifications.
	28	Same	Gross	Same. Cut and external surface.
	30	Adrenal	MP	Neuroblastoma. Small blue cell tumor with occasional cluster of cells arranged in pseudorosettes with central fibrillar material. The cells have indistinct cytoplasmic borders, round or oval nuclei and densely clumped chromatin.
	31	Same	MP	Same. Neuroblastomas, ganglioneuroblastomas, and ganglioneuromas are neoplasms arising from neuroepithelium showing different degrees of differentiation.
	32	Same	HP	Same. Histology is less useful in predicting the prognosis in neuroblastomas than location, age, staging an dpresence of oncogenes. It is useful in separating out the benign ganglioneuroma.

Pediatric Pathology cont.