Pathology Review Carousel 17
Pathology Review Carousel 18
Liver (Gastrointestinal 2 Lab)
Image
 Slide # Tissue Mag Feature
1 Liver LP Normal liver architecture with several portal trats and central veins.
2 Liver MP Normal portal tract and central vein
3 Liver Gross Normal liver
4 Liver LP Needle biopsy, prominent macrovesicular fatty metamorphosis
5 Liver MP Macrovesicular fatty metamorphosis
6 Liver HP Macrovesicular fatty metamorphosis, neutrophils, Mallory's hyalin
7 Liver HP Same as 7
8 Liver Same
9 Liver Same, stained darker and Mallory's hyalin more clearly defined in cytoplasm of hepatocytes.
10 Liver Gross Cut surface, alcoholic hepatitis, green color from bile pigment
11 Liver Gross Cut surface, micronodular portal cirrhosis, small yellow nodules are regenerating nodules containing fat, green color in background is bile indicating possible alcoholic hepatitis as well
12 Liver Gross External surface, micronodular portal cirrhosis
13 Liver Gross Cut surface of liver in slide 13. Yellow color of some nodules indicated presence of fatty metamorphosis
14 Liver LP Cirrhosis, with monolobular pattern of some nodules still retaining central veins. Portion of larger nodule in lower field.
15 Liver MP Large area of fibrosis showing hepatic arteries, portal vein branches, lymphocytic infiltrate and loss of bile ducts.
16 Liver HP Showing portal vein, hepatic artery and now accompanying bile duct.
17 Liver HP Another portal area showing vessels and inflammatory cells, with some cholestasis, but no bile ducts.
18 Liver MP Lobule showing hepatocytes around central vein and some cholestasis
19 Liver HP Hepatocytes showing cholestasis, canalicular plugs, bile in Kupffer cells, and central vein lower right hand corner.
20 Liver LP Needle biopsy, showing acute bridging lesion
21 Liver MP Acute bridging lesion and lobular unrest
22 Liver MP Lobular unrest, with hepatocyte swelling, regeneration, Kupffer cell hypertrophy and hyperplasia, cholestasis and inflammation
23 Liver HP Lobular unrest. Acidophilic body left center
24 Liver HP Lobular unrest, bile-stained cell in center
25 Liver Gross External surface, massive hepatic necrosis, wrinkled capsule, red color from red blood cells in sinusoids with no hepatocytes remaining.
26 Liver LP Needle biopsy of liver with irregular broad bands of fibrosis transecting biopsy and encircling a few small regenerating nodules, partially encircling multilobular nodules
27 Liver LP Showing broad band of fibrosis with inflammation on left with piecemeal necrosis at interface with hepatocytes.
28 Liver LP Bands of fibrosis with piecemeal necrosis transecting biopsy
29 Liver HP Margin of fibrous tissue and hepatocytes showing moderate activity with piecemeal necrosis
30 Liver HP Margin of fibrous tissue and hepatocytes in quiescent area of minimal to no activity
31 Liver Gross External surface of liver, macronodular postnecrotic cirrhosis
32 Liver Gross Cut surface, macronodular postnecrotic cirrhosis
33 Liver Gross Cut surface, macronodular postnecrotic cirrhosis
34 Liver LP Needle biopsy of liver showing blue inflammatory cells outlining enlarged portal tracts
35 Liver MP Portal tract showing stellate "maple leaf" pattern of chronic active hepatitis with extensive piecemeal necrosis and loss of limiting plates.
36 Liver HP Margin of portal tract showing inflammation (predominantly lymphocytes) and piecemeal necrosis
37 Liver HP Same
38 Liver HP Acidophilic (apoptotic) bodywith pyknotic nucleus in center of hepatocytes in lobule
39 Liver Gross Cut surface of liver, chronic passive congestion (CPC)
40 Liver LP CPC, showing portal tract and central area with blood in sinusoids and thinning of centrilobular liver plates
41 Liver HP CPC, centrilobular area with blood in sinusoids and thin liver plates
42 Side view of patient with massive ascites and ecchymoses of arm
43 Spider angioma (nevus) in skin
44 Gross Opened esophagus and upper stomach showing esophageal varices
45 Liver Gross Cut surface, with focal nodular hyperplasia in otherwise normal liver
46 Liver Gross Cut surface of cirrhotic liver containing large green (bile stained) hepatocellular caracinoma at left with intravascular spread
47 Liver MP Hepatocellular carcinoma
48 Pancreas LP Acute pancreatitis. Necrotic area appears granular and blue. Note small focus of hemorrhage.
49 Pancreas MP Acute pancreatitis. Note early fat necrosis with granular pink material within ghosts of fat cells and more extensive hemorrhage.
50 Pancreas HP Acute pancreatitis. Necrotic pancreas is seen as granular purple material. Fat necrosis with some cells containing more basophilic material indicating the presence of calcium that has combined with free fatty acids to form soaps.
51 Pancreas Gross Severe acute hemorrhagic pancreatitis. Edematous (swollen) with extensive hemorrhage (dark purplish-black)
52 Pancreas Gross Acute interstitial pancreatitis. Cross section of pancreas showing small chalky white foci of fat necrosis and some edema (slight bulging from the cut surface).
53 Pancreas Gross Chronic pancreatitis. Note the pancreas is somewhat small with grayish white fibrous areas. There is also a small pseudocyst which is opened.
54 Gallbladder, slide 127 MP Acute and subacute cholecystitis, with mucosa showing ulceration. Note acute inflammation and fibrin in the ulcer.
55 Gallbladder MP Acute and subacute cholecystitis. This area shows marked thickening of the wall with inflammation and some early fibrosis.
56 Gallbladder HP Acute and subacute cholecystitis. Ulcerated mucosa with disrupted epithelium, inflammatory exudate (inflammatory cells and fibrin).
57 Gallbladder HP Acute and subacute cholecystitis. Granulation tissue (fibroblasts and capillaries in ground substance) with little collagen formation as yet. Note edema (from acute inflammation), active fibroblasts, eosinophils and some chronic inflammatory cells.
58 Gallbladder Gross Acute and chronic cholecystitis. Wall thickened from fibrosis, mucosal ulceration and hemorrhage.
59 Gallbladder Gross Pure cholesterol stone in gallbladder that is normal except for cholesterolosis (yellowish streaks in gallbladder mucosa).
60 Gallbladder Gross Multiple pigment stones. Black stones with irregular or spiculated surface (jack stones).
61 Gallbladder Gross Chronic cholecystitis (mucosa is ridged and wall thickened) with multiple mixed stones (stones have multiple smooth, flat surfaces). Bile stained common bile duct can be seen emptying into duodenum.
62 Pancreas Gross Scirrhous adenocarcinoma in the head of the pancreas. Pancreatic carcinoma often stimulate a marked fibrous response giving the tumors the hard, gray white gross appearance.
63 Pancreas Gross Adenocarcinoma in tail of pancreas. The poorlydefined gray-white area is the carcinoma.
64 Liver Gross Non-cirrhotic liver with scirrhous metasteses from pancreatic carcinoma. (Umbilication, indentation of tumors on the liver surface are often found with metastatic carcinomas from many sites: whereas, primary hepatocellular carcinomas usually have little fibrous tissue and so do not umbilicate.) Greenish areas represent cholestatsis from tumor obstructing bile ducts.
65 Mesentery Gross Implantation metasteses from adenocarcinoma arising from the tail of the pancreas.
66 Liver and duodenum Gross Carcinoma of the extrahepatic bile ducts showing massive direct extension or invasion into the liver as well as separate metastases. The dark green is from extensive cholestasis from bile duct obstruction.
67 Duodenum Gross Papillary carcinoma of the ampulla of Vater seen in the opened common bile duct. The probe is in the pancreatic duct.