Image
|
Slide # |
Tissue |
Mag |
Feature |
 |
45 |
Rectum |
Gross |
Adenocarcinoma arising at anorectal junction. Note this carcinoma is ulcerated. (It may have arisen from a villous adenoma). |
 |
46 |
Colon, fixed |
Gross |
Adenocarcinoma, cross section. Note the tumor appears white due to the fibrosis the tumor has elicited and can be seen to invade through the muscularis propria into the subserosa. |
 |
47 |
Appendix |
LP |
Acute appendicitis, ulceration of mucosal surface. |
 |
48 |
Appendix |
HP |
Acute appendicitis, inflammatory exudate with many neutrophils. |
 |
49 |
Appendix |
Gross |
Normal appendix on right, note shiny serosa. Acute appendicitis on left, with serosal hyperemia and fibrinopurulent exudate (friable, tan-yellow, dull). |
 |
50 |
Small Intestine |
LP |
Crohn's disease. Thickened small intestine with chronic inflammation extending into muscularis propria. |
 |
51 |
Small Intestine |
LP |
Crohn's disease. Fibrosis and chronic inflammation extending into serosa (transmural inflammation). While granulomatous inflammation is not clearly identified in this case, it is often present and is a helpful histologic feature. |
 |
52 |
Small Intestine |
HP |
Crohn's disease. Focus showing chronic inflammation and fibrosis. |
 |
53 |
Small Intestine |
Gross |
Crohn's disease. Encroachment of mesenteric fat over the bowel surface. |
 |
54 |
Small Intestine |
Gross |
Crohn's disease. Shows segmental involvement and marked thickening of the bowel wall characteristic of Crohn's disease. Note dilatation of the proximal small intestine, secondary to obstruction from the narrowed segment, is difficult to see. |
 |
55 |
Small Intestine |
Gross |
Crohn's disease. Note the markedly thickened, stiff wall (garden hose appearance) that has resulted from the transmural inflammation and fibrosis. Tooth picks are required to hold the lumen open. |
 |
56 |
Small Intestine |
Gross |
Crohn's disease. Cross section of inflammatory mass formed of loops of small bowel fibrosed together. |
 |
57 |
Colon |
Gross |
Ulcerative colitis. Anorectal junction on the left. Mucosa completely ulcerated and hemorrhagic but not thickened. Note the changes are diffuse and not segmental. |
 |
58 |
Colon |
LP |
Ulcerative colitis. Island of residual mucosa forming inflammatory pseudopolyp. |
 |
59 |
Sigmoid Colon |
Gross |
Luminal surface of sigmoid colon. Note parallel rows of openings to diverticula adjacent to the taeniae coli. |