Pathology Review
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Female Reproductive II
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Image |
Slide # |
Tissue |
Mag |
Feature |
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1 |
Fallopian Tube |
Gross |
Ectopic (tubal) pregnancy. Fetus with anmiotic cavity and hemorrhagic tissue consistent with placental tissue. Note location in the distal (to middle) third of the tube (most common location). |
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2 |
Fallopian Tube |
Gross |
Ectopic (tubal) pregnancy. Black (hemorrhagic) tissue consistent with placental tissue and blood clot in distal one third of falllopian tube. Note no fetal tissue is identifiable as is often the case. |
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3 |
Fallopian Tube |
LP |
Ectopic (tubal) pregnancy. Wall of fallopian tube with stretched fimbriae, hemorrhage, and pale placental villi. |
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4 |
Fallopian Tube |
MP |
Ectopic (tubal) pregnancy. Mucosa and lumen of the fallopian tube with columnar epithelium and villi lined by cyto- and syncytial trophoblastic cells. |
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5 |
Fallopian Tube |
HP |
Same. Note inner layer of pale of cytotrophoblasts and outer eosinophilic layer of syncytial trophoblasts. |
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6 |
Ovary |
Gross |
Dermoid cyst (mature cystic teratoma). Note rounded protuberances (mamillae or Rokitansky's protuberances) from which white structures (teeth) protrude. Also note the yellow-tan greasy materail which is sebaceous material and poorly sen hairs. |
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7 |
Ovary |
Gross |
Dermoid cyst (mature cystic teratoma). Note rounded protuberances, mamillae or Rokitansky's protuberances. The gray-tan areas may represent sebacous material. |
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8 |
Ovary |
LP |
Dermoid cyst (mature cystic teratoma). Note skin like areas with epidermis and sebaceous glands as well as other foci of surface pseudostratified columnar epithelium and deep foci of smooth muscle. |
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9 |
Ovary |
LP |
Dermoid cyst with epidermis and pilosebaceous structures. |
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10 |
Ovary |
HP |
Same. Also note ducts resembling eccrine sweat glands. |
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11 |
Uterus and adnexa |
Gross |
Bilateral serous cystadenomas. (Cannot make the diagnosis on this photo alone). |
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12 |
Ovary |
Gross |
Serous cystadenoma. Note the characteristic thin walled, multilocular cyst (may also be unilocular) usually contains watery fluid. |
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13 |
Ovary |
LP |
Serous cystadenoma. Unilocular cyst lined by single layer of epithelial cells which in some areas resemble fallopian tube or may be flattened (pink area is collagen in the wall). |
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14 |
Ovary |
LP |
Serous cystadenoma. Multilocular cyst. |
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15 |
Ovary |
MP |
Serous cystadenoma. Multilocular cyst lined in some foci by low cuboidal or by flattened epithelial cells. One space lined by columnar epithelium suggestive of fallopian tube (ciliated, non-ciliated and peg cells). Note pale pink area is a corpora albicans. |
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16 |
Ovary |
Gross |
Serous cystadenocarcinoma. Note that the cyst contains papillary and solid areas. |
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17 |
Ovary |
Gross |
Serous cystadenocarcinoma. Note the cyst has numerous papillary projections which form a relatively solid area. There is focal hemorrhage. |
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18 |
Omentum |
Gross |
Implantation metastases. Multiple small serosal nodules in the omentum. This was from an ovarian cystadenocarcinoma, but there are no gross features that allow that diagnosis. |
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19 |
Ovary |
LP |
Serous cystadenocarcinoma. Note the papillary areas and the more invasive glandular areas. |
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20 |
Ovary |
MP |
Serous cystadenocarcinoma. Note papillary foci (central fibrovascular stalk covered by epithelial cells) and the invasive area of poorly formed glands. |
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21 |
Ovary |
HP |
Serous cystadenocarcinoma. Area of poorly formed glands with irregular often slit-like lumens. |
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22 |
Ovary |
HP |
Serous cystadenocarcinoma. Papillary area with some large and some fine papillae and psammoma bodies. This area alone would be difficult to distinguish from a borderline tumor. |
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23 |
Ovary |
LP |
Borderline tumor. Note papillary structures ont he cyst lumen and the ovarian surface (peritoneal serous proliferations). Note the absence of destructive stromal invasion. |
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24 |
Ovary |
LP |
Borderline tumor. In this area the ovarian surface (peritoneum) is free of proliferations. The papillary projections are in the cyst lumen. |
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25 |
Ovary |
MP |
Borderlinen tumor. Papillary configuration with slight epithelial tufting. |
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26 |
Ovary |
MP |
Borderline tumor. Extensive epithelial tufting typical of borderline tumor. |
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27 |
Uterus |
Gross |
Adenomyosis (endometrial glands and stroma extending into the myometrium for more than 1/2 low power field). Typical appearance of section of uterus with adenomyosis showing thickened myometrium (especially posteriorly) and trabeculation and hemorrhagic foci. |
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28 |
Ovary |
Gross |
Endometriosis. Cross section of multiple chocolate cysts (often more brown than black). |
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29 |
Placenta |
Gross |
Complete Hydatidiform Mole. Note appearance similar to clusters of grapes (swollen chorionic villi). |
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30 |
Breast |
Gross |
Breast carcinoma. Note large irregular mass distorting one quadrant of breast and nipple. |
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31 |
Woman |
Gross |
Breast carcinoma. Note nipple retraction and distortion of skin of left breast. |
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32 |
Breast |
Gross |
Breast carcinoma. Note firm, white irregularly demarcated area with radiating pattern typical of scirrhous, invasive ductal (adeno)carcinoma. |
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33 |
Breast |
LP |
Breast carcinoma, invasive ductal (adeno)carcinoma. Note cords and tubules haphazardly infiltrating desmoplastic (dense collagen) stroma. |
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34 |
Breast |
LP |
Same. |
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35 |
Breast |
MP |
Breast carcinoma, invasive ductal (adeno)carcinoma. Note some larger nests of tumor and the infiltration of fat. |
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36 |
Breast |
HP |
Same. Nests of malignant ductal cells. Note nuclear irregularity. |
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37 |
Breast |
Gross |
Fibroadenoma. Circumscribed, white rubbery nodule with slit-like spaces. |
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38 |
Breast |
LP |
Fibroadenoma. circumscribed, nodule well demarcated from surrounding breast tissue composed of fibrous tissue and ducts. |
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39 |
Breast |
MP |
Fibroadenoma. Fibrous tissue with slit-like compressed ducts. |
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40 |
Breast |
Gross |
Fibrocystic changes. irregular firm white foci (fibrosis) and cysts. |
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41 |
Breast |
LP |
Fibrocystic changes. Macro and microscopic cysts and fibrosis are features most easily seen at this mag. |
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42 |
Breast |
MP |
Fibrocystic changes. Two cysts. One lined by apocrine metaplasia (large cells with abundant eosinophilic cytoplasm). |
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43 |
Breast |
HP |
Same. |
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44 |
Breast |
HP |
Fibrocystic changes. Focus with microcalcification. |
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45 |
Breast |
MP |
Fibrocystic changes. Mild ductal epithelial hyperplasia. Ducts are lined by epithelium more than 2 cell layers thick. |